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Sunday, 15 Jun 2025

Publications

Discover how our Dr. Oligo Synthesizers
are helping researchers achieve remarkable results
in peer-reviewed, high-impact journals

Trusted by Researchers Worldwide

At Biolytic Lab Performance, our Dr. Oligo DNA and RNA synthesizers have been relied upon by top research institutions and companies for groundbreaking studies.

This page provides direct links to scientific publications that feature our products, demonstrating their reliability and value in various scientific fields.

Explore the research and see how Biolytic’s cutting-edge technology supports innovation across the globe.

Journals

Dr. Oligo | Low and Medium Throughput

Systematic Evaluation of Position-Specific Tolerability of Seven Backbone and Ribose Modifications in Fully Chemically Stabilized siRNAs

nucleic acid therapeuticsVol 0 Iss 0, May 26, 2025

Dr. Oligo 48

2025

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

Multispecies-targeting siRNAs for the modulation of JAK1 in the skin

BRIEF REPORT| VOLUME 35, ISSUE 1, 102117, MARCH 12, 2024

Dr. Oligo 48

2024

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

EZH2 inhibition reactivates epigenetically silenced FMR1 and normalizes molecular and electrophysiological abnormalities in fragile X syndrome neurons

Front. Neurosci., 20 February 2024

Dr. Oligo 48

2024

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo

Nucleic Acids Research, Volume 52, Issue 2, 25 January 2024, Pages 977–997,

Dr. Oligo 48

2024

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin

Nature Communications volume 14, Article number: 7099 (2023)

Dr. Oligo 48

2023

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

Targeted genome editing with a DNA-dependent DNA polymerase and exogenous DNA-containing templates

Nature Biotechnology (2023)

Dr. Oligo 48

2023

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

Antisense oligonucleotide rescue of CGG expansion–dependent FMR1 mis-splicing in fragile X syndrome restores FMRP

PNAS (2023)

Dr. Oligo 48

2023

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington’s disease

Molecular Therapy

Dr. Oligo 48

2023

Affiliation: University of Massachusetts Chan Medical School

Genome-wide detection of CRISPR editing in vivo using GUIDE-tag

Nature Communications volume 13, Article number: 437 (2022)

Dr. Oligo 48

2022

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington’s disease models

Nature Communications volume 13, Article number: 5802 (2022)

Dr. Oligo 48

2022

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

Small activating RNA activation of ATOH1 promotes regeneration of human inner ear hair cells

Bioengineered Volume 13, 2022 - Issue 3

Dr. Oligo 48

2022

Affiliation: Peking Union Medical College and Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing, China

Phosphonoacetate Modifications Enhance the Stability and Editing Yields of Guide RNAs for Cas9 Editors

Biochemistry 2023, 62, 24, 3512–3520

Dr. Oligo 48

2022

Affiliation: Agilent Research Laboratories, Santa Clara, California 95051, United States

G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects

Nucleic Acids Research, Volume 50, Issue 22, 9 December 2022, Pages 12657–12673

Dr. Oligo 48

2022

Affiliation: University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA

Implications of N7-hydrogen and C8-keto on the base pairing, mutagenic potential and repair of 8-oxo-2′-deoxy-adenosine: Investigation by nucleotide analogues

Bioorganic Chemistry Volume 127, October 2022, 106029

Dr. Oligo 48

2022

Affiliation: State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266237, China

A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites

Proceedings of the National Academy of Sciences doi: 10.1073/pnas.2202842119

Dr. Oligo 48

2021

Affiliation: Department of Molecular Neurobiology, Max Planck Institute of Experimental Medicine, Göttingen, Germany, University of Göttingen, Germany

Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide

Nature Medicine

Dr. Oligo 48

2021

Affiliation: University of Massachusetts Medical School, Worcester, MA, USA

High-resolution DNA quadruplex structure containing all the A-, G-, C-, T-tetrads

Nucleic Acids Research, Volume 46, Issue 21, 30 November 2018, Pages 11627-11638

Dr. Oligo 48

2018

Affiliation: State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Biochemistry, School of Life Sciences, Fudan University, Shanghai 200433, China

Improving CRISPR–Cas specificity with chemical modifications in single-guide RNAs

Nucleic Acids Research, Volume 46, Issue 2, 25 January 2018, Pages 792–803,

Dr. Oligo 48

2017

Affiliation: Agilent Research Laboratories, Santa Clara, CA, USA

Dr. Oligo | High and Ultra High Throughput

Heterovalent Click Reactions on DNA Origami

Bioconjugate Chemistry

Dr. Oligo 192c

2025

Affiliation: Massachusetts Institute of Technology

Modern Approaches to de novo Synthesis of Extended DNA Fragments: Assembly of a Wide Repertoire of Sequences

ActaNaturae Issue: Vol 16, No 1 (2024)

Dr. Oligo 768XLc

2024

Affiliation: Research Institute for Systems Biology and Medicine, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine

WO2023/175091A2 – MAPT siRNA and uses thereof

Patent Cooperation Treaty (PCT) Publication

Dr. Oligo 192

2023

Affiliation: JANSSEN PHARMACEUTICA NV

Phosphonoacetate Modifications Enhance the Stability and Editing Yields of Guide RNAs for Cas9 Editors

Biochemistry 2023, 62, 24, 3512–3520

Dr. Oligo 96

2022

Affiliation: Agilent Research Laboratories, Santa Clara, California 95051, United States

Enhancing Antitumor Efficacy of Nucleoside Analog 5-Fluorodeoxyuridine on HER2-Overexpressing Breast Cancer by Affibody-Engineered DNA Nanoparticle

International Journal of Nanomedicine

Dr. Oligo 96

2020

Affiliation: Hebei University, Baoding 071002, People’s Republic of China

The microRNA-200 cluster on chromosome 23 is required for oocyte maturation and ovulation in zebrafish†

Biology of Reproduction, Volume 103, Issue 4, October 2020, Pages 769–778,

Dr. Oligo 192

2020

Affiliation: Huazhong Agricultural University, Wuhan, China

Affibody-Conjugated RALA Polymers Delivering Oligomeric 5-Fluorodeoxyuridine for Targeted Therapy of HER2 Overexpressing Gastric Cancer

Macromolecular Bioscience Volume20, Issue7 July 2020 2000083

Dr. Oligo 96

2020

Affiliation: Hebei University, Baoding, 071002 China

Co-delivery of 5-fluorodeoxyuridine and doxorubicin via gold nanoparticle equipped with affibody-DNA hybrid strands for targeted synergistic chemotherapy of HER2 overexpressing breast cancer

Nature Scientific Reports volume 10, Article number: 22015 (2020)

Dr. Oligo 96

2020

Affiliation: Hebei University, Baoding, 071002 China

Bioinformatic analyses of a potential Salmonella-virus-FelixO1 biocontrol phage BPS15S6 and the characterisation and anti-Enterobacteriaceae-pathogen activity of its endolysin LyS15S6

Antonie vaan Leeuwenhoek Journal of Microbiology

Dr. Oligo 192

2019

Affiliation: Guizhou Education University, Guiyang, 550018, Guizhou Province, China

Biodegradation of Insecticide Monocrotophos by Bacillus subtilis KPA-1, Isolated from Agriculture Soils

Applied Biochemistry and Biotechnology

Dr. Oligo 96/192

2015

Affiliation: Biogas Research and Extension Centre, Department of Microbiology, Gujarat Vidyapith, Sadara, Gandhinagar, Gujarat, 382 320, India

High-throughput RNA profiling via up-front sample parallelization

Nature Methods

Dr. Oligo 192

2015

Affiliation: Yale University School of Medicine, New Haven, Connecticut, USA

Biodegradation of Insecticide Monocrotophos by Bacillus subtilis KPA-1, Isolated from Agriculture Soils

Applied Biochemistry and Biotechnology

Dr. Oligo 96/192

2014

Affiliation: Gujarat Vidyapith, Sadara, Gandhinagar, Gujarat, 382 320, India

Systematic screens of proteins binding to synthetic microRNA precursors

Nucleic Acids Research, Volume 41, Issue 3, 1 February 2013, Page e47,

Dr. Oligo 96

2012

Affiliation: Institute of Pharmaceutical Sciences, ETH Zürich, Eurofins MWG Operon, University of Surrey, Guildford, Surrey

Legacy Oligo Synthesizers and General Dr. Oligo |

Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

Nature Communications volume 15, Article number: 795 (2024)

Dr. Oligo

2024

Affiliation: Massachusetts Institute of Technology

Tumor-Associated Enzyme-Activatable Spherical Nucleic Acids

ACS Nano 2022, 16, 7, 10931–10942

ABI 394

2022

Affiliation: Northwestern University

Detection of fluorescence-labeled DNA with in-plane organic optoelectronic devices

Biomedical Optics Express Vol. 13, Issue 12, pp. 6300-6316 (2022)

ABI 3900

2022

Affiliation: Kiel University

Towards Practical and Robust DNA-Based Data Archiving Using ‘Yin-Yang Codec’ System

Nature Computational Science doi: 10.1038/s43588-022-00231-2

Dr. Oligo

2021

Affiliation: BGI-Shenzhen, Shenzhen 518083, China, George Church Institute of Regenesis, BGI-Shenzhen, Shenzhen, 518120, China

Anti-intoxication and protective effects of a recombinant serine protease inhibitor from Lentinula edodes against acute alcohol-induced liver injury in mice

Applied genetics and molecular biotechnology Published: 19 April 2020

Dr. Oligo

2020

Affiliation: Wuhan Institute of Technology

Effect of Chemical Modifications on Aptamer Stability in Serum

Nucleic Acid TherapeuticsVol. 27, No. 6

Expedite 8909

2017

Affiliation: Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York.

Farnesoid X receptor regulates SULT1E1 expression through inhibition of PGC1α binding to HNF4α

Biochemical Pharmacology

Dr. Oligo

2017

Affiliation: College of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, China

Construction and characterization of an infectious replication competent clone of porcine endogenous retrovirus from Chinese miniature pigs

Virology Journal Volume 10, Article number 228

ABI 3700

2013

Affiliation: West China School of Pharmacy, Sichuan University, Chengdu, 610041, China

An Antibody-Based Molecular Switch for Continuous Biosensing

biorxiv

Expedite 8909

2013

Affiliation: Stanford University, Stanford, CA 94305, USA

Chronic Corticosterone Administration Dose-Dependently Modulates Aβ(1–42)− and NMDA-Induced Neurodegeneration in Rat Magnocellular Nucleus Basalis

Journal of Neuroendocrinology Volume 12, Issue 6

ABI 430 A

2001

Affiliation: University of Groningen, the Netherlands