Developed For Efficiency,
Tested For Consistency
Explore Controlled Flow
Controlled Flow

Here at Biolytic, we are continuously looking for ways to improve the oligo synthesis process to better meet our customers' needs. From small research laboratories, to production ready facilities, the demand for standard DNA/RNA oligos and complex custom oligos using special reagents is increasing. With this in mind, we developed Controlled Flow synthesis consumables with adjusted flow rates to make it easier for you to achieve optimal coupling times needed for a successful synthesis.

Why Choose Controlled Flow?

Successful DNA RNA oligonucleotide synthesis and high-quality, full-length oligos start with quality synthesis consumables. Using customer feedback and experimental data, we have developed a new standard for oligo synthesis consumables, capable of more full-length oligos and increased synthesis accuracy.
Inconsistent synthesis consumables with unknown flow rates bring uncertainty into your experiments and can lead to hard to diagnose errors in synthesis, reduced coupling efficiency, reagent waste, and unstable experiment data.
Biolytic's Controlled Flow synthesis consumables are quality inspected and lot tracked for a guaranteed consistent flow rates, so you can be confident your synthesis is off to a successful start. Our Controlled Flow synthesis consumables are compatible with all DNA RNA oligonucleotide synthesizers that use synthesis columns, 96-well plates, or 384-well plates. With the appropriate synthesis protocol, Controlled Flow synthesis consumables can be used to successfully synthesize a variety of different molecules.
Key Features
- Guaranteed consistent matched flow rates across all columns and plates
- Increased synthesis accuracy and reduced failure rates
- Can be used on all supported synthesizers *
- Quality inspected and controlled
- Lot tracked
*May require protocol modifications
Increasing Coupling Efficiency

Increasing coupling efficiencies yields more full-length oligos. Biolytic's Controlled Flow synthesis consumables are designed to increase coupling efficiency, utilizing optimized flow rates for your applications. Our synthesis consumables allow for successful DNA amidites coupling that require short coupling time AND allow for successful RNA amidites coupling that require long coupling time.

Reduced Synthesis Cost

Biolytic Controlled Flow synthesis consumables are designed with adjusted coupling times to make the synthesis process more cost effective by reducing the amount of synthesis reagents used during a cycle saving money and resources.

Quality Controlled

All synthesis consumables pass a rigorous quality control process to ensure efficient and consistent DNA / RNA oligo production. Synthesis consumables are certified to be tested and meet or exceed all factory documented specifications and are ready for synthesis.

  • - Synthesis Success Rates
  • - Consistent Flow Rates
  • - Increased Reaction Efficiency
  • - Rigorous Quality Control Process

Biolytic's Controlled Flow synthesis consumables are tested and optimized for use with the Dr. Oligo line of DNA/RNA oligo synthesizers. The synthesis consumables are also compatible with other DNA/RNA oligo synthesizers that use synthesis columns, 96-well synthesis plates or 384-well synthesis plates.

If you are synthesizing:
Dr. Oligo 48
CF Consumables

Dr. Oligo 192XLc
CF Consumables

96-Well Plates*
*Requires Request a Quote
Dr. Oligo 768XLc
CF Consumables

384-Well Plates
CF Consumables

384-Well Plates
Biolytic's Controlled Flow consumables are compatible with any DNA/RNA oligo synthesizers that use synthesis columns, 96-well synthesis plates, or 384-well synthesis plates including but not limited to:
  • ABI 3900
  • Northwest 3900
  • Biolytic 3900
  • Dr. Oligo 96, 96e
  • Dr. Oligo 192, 192e
  • Dr. Oligo 384, 384e
  • Dr. Oligo 768, 768e
Explore Our Offerings

Biolytic's Controlled Flow synthesis consumables are quality tested and optimized for synthesis chemistries requiring either shorter and/or longer coupling times.

*Requires Request a Quote

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