Fitting synthesis columns into a 96 well rack has traditionally involved pressing each column into each hole. In order to create a tight seal the column needs to be flush with the top of the rack. Performing this operation by hand can lead to sore fingers overtime. In many cases people opt to forcefully pound the columns in with a hammer. Both methods are time consuming and in the case of using a hammer, it can cause serious damage to the synthesis rack and/or synthesis columns.
The Biolytic Column Press solves these issues with a simple economical product that allows for fast, easy fitment and removal of synthesis columns into a 96 well rack without damage to the rack or columns. These synthesis racks are typically used in dna synthesizers, rna synthesizers, oligo synthesizers and with oligo purification. To insert columns into the rack, simply place the rack with loosely fitted columns on the removable plate and slide the plate into the column press. Position the plate so the first set of columns are properly in line with the press. Push down on the handle until the columns are firmly seated. Repeat the process until all the columns in the rack have been pressed.