Frequently Asked Questions
Biolytic designs, manufactures, and services the most advanced DNA RNA oligonucleotide synthesizers in the world.
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If you have any questions about your Dr. Oligo dna synthesizer, rna synthesizer, Biolytic oligo synthesis accessories, or any general inquiries, contact us! |
Our customers come from all over the world, researching a variety of topics. We have a wide range of customers in pharmaceutical, biopharmaceutical, university labs, government institutions, research facilities, startups, and oligo synthesis companies.
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Dr. Oligo products (dna synthesizers and rna synthesizers) and services are designed and manufactured by Biolytic Lab Performance, Inc. Dr. Oligo is a trademark of Biolytic Lab Performance, Inc.
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If you would like to return parts from your DNA synthesizer, RNA synthesizer, or other, please see our return policies here. |
We accept a variety of different payment options. See our full list of payment options on our policies page here |
Please reach out to our sales team for any purchasing inquiries for known Part Numbers
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We ship worldwide. Please see our international policy here |
When required by law, Biolytic will collect Federal, State and/or Local sale, use, excise, and other taxes that apply to a Customer's shipment. These taxes are in addition to the purchase price of the Products subject to an order. Customer will remit the correct tax unless Customer is tax exempt and Biolytic has a valid signed tax exemption certificate on file. |
All of our DNA RNA oligonucleotide synthesizers, synthesis and post synthesis accessories, and software are designed and manufactured in Fremont, California. |
Yes, our DNA synthesizers / RNA synthesizers can use standard A, T, C, G phosphoramidites, as well as specials for 3'-, 5'-, and internal modifications, dyes such as FAM or cyanine dyes (Cy4, Cy5, etc), biotin, LNAs, backbone modifications, and more. |
Our DNA synthesizers and RNA synthesizers use standard synthesis columns and synthesis 96-well and 384-well plates. We offer our own Biolytic Lab Performance, Inc. line of synthesis consumables that have been tested and verified to work, but third party synthesis consumables will work as well.
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Our Dr. Oligo DNA RNA oligonucleotide synthesizers may be installed in laboratories that have a vent, a source of 100 psi of inert gas, and power supply of 110V - 240V, 50-60Hz.
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DNA synthesis, RNA synthesis, and post synthesis accessories are sold separately.
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We offer medium (48 oligos in a run), high throughput (192 oligos in a run), and ultra high throughput (768 oligos in a run) DNA RNA oligo synthesizers. The number of oligos synthesized per day depends on your DNA synthesizer / RNA synthesizer throughput, as well as the length of your oligos. |
Our DNA oligo synthesizers and RNA oligo synthesizers are highly customizable to fit your needs. Prices vary based on instrument configuration.
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The price per base is dependent on the price paid for reagents. We can provide the volume per reagent needed to add one base. To determine
the price per base, you will multiple the price of reagent by the volume needed. These volumes are based on using our protocols and our synthesis columns.
Volumes may vary depending on your protocol or synthesis consumables.
REAGENTS
Deblock (3% TCA in DCM)
Per Cycle
500 to 600 ul (Dblk vol. is increased for later cycles)
Total Volume per 20-mer
10 mL
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Instruments require a stable temperature environment. This means we do not want the temperature changing a lot (+ / - 5 degrees C is fine).
No matter which DNA synthesizer / RNA synthesizer you choose, the reagents need to be kept dry and free of atmosphere contaminants such as
water and oxygen (higher than 20%).
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We have a variety of service options and packages depending on your needs.
Please visit our Service Plans page for more information about dna synthesizer and rna synthesizer maintenance services, and support |
Our website www.biolytic.com lists most of our spare parts. An average annual cost to maintain the instrument is
6% to 12% of the USA list price. This is highly dependent on your use case, and how you decide to perform maintainence on your instrument.
The older the instrument, the more the cost increases as more things wear out. There will be components like gaskets, filters, tubing and valves that will need to be regularly replaced or maintained. Preventative maintenance is recommended to keep your instrument running smoothly.
Please visit our Service Plans page for more information. |
Our technical support team is ready to help you with any questions you may have about DNA RNA oligo synthesis or your dna synthesizer / rna synthesizer.
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Our team of application specialist and chemists are available for any chemistry, synthesis, or applications questions you may have.
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Maintenance is based on your usage. There will be components like gaskets, filters, tubing and valves that will need to be regularly replaced or maintained. Preventative maintenance is recommended to keep your instrument running smoothly. |
Check out our introduction to the chemistry behind oligo synthesis here: Introduction to Oligonucleotide Synthesis |